Mavrox treatments — Performax, Tadalafix, and Xtend — are prescription medications, and not everyone is a good candidate for them. A licensed provider reviews your health history before prescribing, but it's important to understand upfront who these treatments are not appropriate for, and what warning signs mean you should stop and seek medical attention.
General precautions
Regardless of which product you're considering, you should not take Performax, Tadalafix, or Xtend if any of the following apply to you:
You are a woman, or under 18 years of age.
You take nitrates in any form (including recreational "poppers") — combining nitrates with these medications can cause a dangerous drop in blood pressure.
You've been advised by a doctor to avoid sexual activity due to a cardiovascular condition.
You take riociguat for pulmonary hypertension.
You should also talk to your provider before starting treatment if you:
Take alpha-blockers or medications for high blood pressure.
Have kidney or liver disease.
Have a history of priapism, sickle cell disease, leukemia, multiple myeloma, or another condition that may increase the risk of prolonged erections.
Have any other medical condition or take medications your provider should consider.
Stop taking the medication and seek emergency medical care immediately if you experience:
An erection lasts more than 4 hours
Sudden vision loss or significant vision changes
Sudden hearing loss
Chest pain during sexual activity
This applies for any Mavrox treatment.
Additional precautions for Performax and Tadalafix (PDE5 inhibitor–based)
Performax and Tadalafix both contain PDE5 inhibitors (Vardenafil and/or Tadalafil). Beyond the general precautions above, these are not appropriate if:
You're currently taking any form of nitrate medication (this bears repeating — it's the most serious interaction risk with these products).
You have low blood pressure, uncontrolled high blood pressure, or certain cardiovascular conditions.
Common, generally mild side effects can include headache, flushing, dizziness, nausea, or nasal congestion.
Additional precautions for Xtend (SSRI-based)
Xtend is different from the other two products because it contains paroxetine, an SSRI — which comes with its own, more significant set of contraindications. In addition to the general precautions above, Xtend is not appropriate if you:
Are currently taking another SSRI, SNRI, or other serotonergic medication.
Have used an MAOI within the past 14 days.
Have a history of bipolar disorder, seizure disorder, or active suicidal ideation.
Combining Xtend with other serotonergic medications or a recent MAOI can cause serotonin syndrome, a serious and potentially life-threatening reaction. You should also tell your provider about any history of depression or self-harm before starting Xtend, since SSRIs can affect mood in ways that need monitoring.
Stop taking Xtend and seek immediate medical attention if you experience:
Signs of serotonin syndrome: agitation, high fever, tremor, or rapid heartbeat.
New or worsening suicidal thoughts, or a worsening mood.
Important: if you're prescribed Xtend, do not stop taking paroxetine abruptly without consulting your provider — stopping an SSRI suddenly can cause withdrawal symptoms and should be done under medical guidance.
Common side effects of Xtend can include nausea, drowsiness, dry mouth, sexual side effects, headache, flushing, or indigestion.
A note on compounded medications
Performax, Tadalafix, and Xtend are compounded medications. Compounded medications are not approved or evaluated for safety, effectiveness, or quality by the FDA. Your provider takes this into account, along with your personal health history, when determining whether treatment is appropriate for you.
This article is for general informational purposes and is not a substitute for professional medical advice. Treatment decisions are always made by a licensed provider based on your individual health history. If you're ever unsure whether a symptom or interaction applies to you, contact your provider before taking your next dose.
Prescription required. Individual results may vary. Compounded medications are not approved or evaluated for safety, effectiveness, or quality by the FDA. Do not take with nitrates or riociguat. Do not stop taking paroxetine without consulting your healthcare provider. Seek medical attention for suicidal thoughts or an erection lasting longer than 4 hours.